The conservation, observation and transport of all living biological or artificial constructions (cells, tissues, organs, small animal) requires perfect metrological control of the environment in which they are embedded (temperature, perfusion, gas pression, gravity), depending on the context of the study, as close as possible to the conditions of physiological/pathological reality. To preserve these precious samples from different cellular stresses (contamination, mortality, hypoxia, etc.) and to collect reliable indicators or markers of biological interest over long culture times (between labs, spatial flight), there is no mobile and autonomous biomedical device that allows both incubation, observation in real time. This investigation concerns the potential of an autonomous thermal incubator (enclosure,insert) allowing the transport, the maintenance of culture conditions by perfusion and the observation at any time and without physical contact of the samples it contains. In its basic version, we developed MIBA as a new and innovative device (Micro Incubator Biomedical Autonomous) as a single-channel perfusion and long-term monitoring of cell culture for transport. We proposed now to perform the multi-channel MIBA to maintain and compare the different growing conditions in real time as : Transport and continuous observation while preserving sterility and optimal conditions for cell and tissue culture; Autonomy and network connectivity for alarm management; Specific environment as Gas Partial pressure/ Temperature monitoring. For this new biomedical device (culture and transport), we have identified a high level of supply which concerns living material (cells, tissues, small organs, small animal) and a new market located on earth, but not only.
